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KMID : 0882419750180100902
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Korean Journal of Medicine
1975 Volume.18 No. 10 p.902 ~ p.917
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A Clinical Study of Endocrine Adrenal Tumors
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Min Hun-Ki
Cho Bo-Youn
Park Young-Bae
Kim Kwang-Won
Kang Chong-Myung
Park Jeong-Euy
Cho Kyoung-Sam
Kim Seong-Yeon
Yu Suck-Hee
Lee Yong-Kook
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Abstract
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The clinical, pathological observation on 12 patients with endocrine adrenal tumor recognized at Seoul National University Hospital from 1969 to May, 1975 were performed and the following results were obtained.
I. Five cases of cushing´s syndrome were diagnosed easily by clinical features and elevated urinary 17-test OCHS amont. Dexamethasone suppression test
and ACTH stimulation test were useful in differentiation between Cushng´s syndrome with adrenal cortical hyperplasia and adrenal cortical tumor. There is no difference in clinical features and other laboratory findings between patients with cortical hyperplasia and cortical tumor.
2. One case of Cushing´s syndrome with adrenal critical modular hyperplasia showed positive dexamethasone suppression test and negative ACTH stimulation test, which suggested that adrenal cortical function was due to ACTH dependency and adrenal cortical autonomy.
3., Two cases of primary aldosteronism had hypertension, hypokalemia and increased urinary K excretion. After spironolactone administration serum K increased more than 1 mEq/L.
4. In four cases of pheochromocytoma preoperative diagnosis were possible except one by clinical findings, elevated urinary vanillylmandelic acid excretion and regitin test. Pathologically two cases were pheochromocytoina and, two cases paraganglioma.
5. All patients with endocrine adrenal tumor improved in clinical and laboratory findings after removal of tumor.
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KEYWORD
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